Transcatheter aortic valve implantation: the evidence is catching up with reality
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Transcatheter aortic valve implantation: the evidence is catching up with reality.
Degenerative aortic stenosis has become the most common valve disease in Europe and the USA due to prolonged life expectancy and associated degenerative effects on cardiac structures. It is caused by an active pathobiological process which entails chronic inflammation with lipoprotein deposition, osteoblast activation, and extracellular calcification with bone formation. Progressive valve obstr...
متن کاملTranscatheter Aortic Valve Implantation
A 97-year-old man was referred for assessment to our transcather aortic valve implantation (TAVI) team. He had suffered multiple hospitalizations for heart failure with a signifi cantly elevated BNP at 1830 pg/mL. At the time of assessment, he had grade IV New York Heart Association (NYHA) symptoms. Until recently, he had been working actively, but this had subsequently been severely limited by...
متن کاملTranscatheter Aortic Valve Implantation
Calcific aortic stenosis (AS) is the most common form of degenerative heart valve disease in developed countries. AS predominantly affects the elderly with a prevalence of 4% in people over the age of 80 years. With increasing longevity and an ageing population the absolute number of people afflicted with AS is set to rise. The clinical course of the disease is insidious at first (Ross & Braunw...
متن کاملTranscatheter aortic valve implantation
Transcatheter aortic valve implantation was developed to offer a therapeutic solution to patients with severe symptomatic aortic stenosis who are not candidates for conventional aortic valve replacement. The improvement in transcatheter aortic valve implantation outcomes is still of concern in the areas of stroke, vascular injury, heart block, paravalvular regurgitation and valve durability. Co...
متن کاملTranscatheter aortic valve implantation
Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK *Email: [email protected] BACKGROUND AND INTRODUCTION Aortic valve (AV) disease is a common condition with its prevalence, particularly aortic stenosis increasing exponentially with advancing age. A decade ago conventional aortic valve replacement (AVR) was the only treatment when medical management failed and symp...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2010
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehq315